The World Cup wasn't won in a day. It took hard work, team integrity, the right moments and a football field of great colonization to score the winning goal. Your most valuable player is your intestinal microbiome in the game of health.
You can improve your health to your optimal level by manipulating your intestinal microbiome with probiotics.
Probiotics are live therapeutic microorganisms that have a beneficial effect on the intestinal mucosa through several mechanisms. Like a restorative paintbrush, probiotics inhibit pathogens from adhering to the gut wall, they make the epithelium wall stronger and less permeable and they keep the immune system in check. The microbiota becomes stable and normal fermentation takes place.
What about inflammation? Does inflammation cause Chronic Fatigue Syndrome? Probably not. A better explanation might be that there is an alteration in the intestinal microbiome that becomes more fertile for pathogens to set up camp and those pathogens create low grade inflammation and cause peripheral pro-inflammatory signaling throughout the body. Think of a pin stuck in a doorbell. The doorbell can't turn off unless someone releases the pin. All you can hear is the frequency of the doorbell ringing. It's almost as if this frequency calls other viruses out of dormancy and various antibodies come into action. This whole "call to arms" becomes exhausting for the host.
How does inflammation effect the gut? Details, details. There are two major nerve centers in the gut. One is called Auerbach's in the muscles and the other is called Meissner's that lives in the submucosa. These nerve centers send and receive messages, crank the muscles into action and talk to each other through intestinal microcircuits. When there is gut inflammation whether permanent or transient the ENS can disrupt normal G.I. functions. Muscular movements and secretions involved in nutrient absorption are changed. When the intestines becomes inflamed nerves get damaged so neurotransmitters or brain chemicals form differently and the system gets flooded with WBC's that rush in to assess the cellular scene. This results in motility issues, pain, and gut dysfunction well after the inflammatory event has been resolved.
Chronic fatigue syndrome is characterized by increased oxidative stress. Chronic autoimmune disease patients have lower levels of a major antioxidant in the body called L-Glutathione. L-Glutathione is rapidly depleted by oxidative stress and this deficiency creates more oxidative stress and disease progression. A vicious cycle ensues. We all have oxidative stress from the foods we eat and environmental exposures, but our body maintains a balance when an ROS or reactive oxygen species is formed then our tissues produce more antioxidants to fight the fire. Sometimes the fire becomes overwhelming when persistent chronic oxidative stress depletes our antioxidant stores. This is when we experience systemic and local tissue injury. We don't have enough water to douse the fire. Chronic disease makes chronic fatigue.
I'm taking the extremely radical step of eliminating a financial barrier that affects almost everyone I see.
